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We agree that the role of an acute illness is important in patients at risk of developing Acute Kidney Injury(AKI). We would also suggest that the development of AKI is highly unpredictable in the course of an acute illness. We recently conducted an audit on patients who developed AKI following an admission due to an acute illness. We identified 9 patients during a 3 month period. We tracked their creatinine levels from admission to the development of AKI(figure) and it was clear that there was no persistent trend to the creatinine levels to warn doctors of the development of AKI. The risk of developing AKI during the course of admission was also highly variable ranging from day 1- 20 of admission.
The physiological state of an acute illness is highly variable and patients at risk of AKI should be monitored closely through out their acute illness with a high degree of suspicion to better prevent AKI.
Re: Safety of coprescribing NSAIDs with multiple antihypertensive agents
Dear Sir
We agree that the role of an acute illness is important in patients at risk of developing Acute Kidney Injury(AKI). We would also suggest that the development of AKI is highly unpredictable in the course of an acute illness. We recently conducted an audit on patients who developed AKI following an admission due to an acute illness. We identified 9 patients during a 3 month period. We tracked their creatinine levels from admission to the development of AKI(figure) and it was clear that there was no persistent trend to the creatinine levels to warn doctors of the development of AKI. The risk of developing AKI during the course of admission was also highly variable ranging from day 1- 20 of admission.
The physiological state of an acute illness is highly variable and patients at risk of AKI should be monitored closely through out their acute illness with a high degree of suspicion to better prevent AKI.
Competing interests: No competing interests