Intended for healthcare professionals

Letters Inhaled corticosteroids for COPD

Authors’ reply to Turgeon and Tejani and to Manderville

BMJ 2012; 345 doi: (Published 20 December 2012) Cite this as: BMJ 2012;345:e8375
  1. Hye Yun Park, visiting research fellow1,
  2. S F Paul Man, professor of medicine2,
  3. Don D Sin, professor of medicine3
  1. 1Institute of Heart and Lung Health (UBC James Hogg Research Center), St Paul’s Hospital, Vancouver, BC, Canada
  2. 2Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Seoul, South Korea
  3. 3Department of Medicine (Respiratory Division), University of British Columbia, Vancouver, BC, Canada
  1. don.sin{at}

As pointed out by Turgeon and Tejani,1 the controversy is considerable on how to optimally calculate the number needed to treat (NNT) for outcomes that subjects can experience multiple times during follow-up. We chose an event based method to calculate the NNT,2 which others have used, to …

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