Imran Aziz clinical research fellow in gastroenterology, Marios Hadjivassiliou consultant neurologist, David S Sanders professor of gastroenterology
Aziz I, Hadjivassiliou M, Sanders D S.
Does gluten sensitivity in the absence of coeliac disease exist?
BMJ 2012; 345 :e7907
doi:10.1136/bmj.e7907
Re: Does gluten sensitivity in the absence of coeliac disease exist?
I enjoyed the paper by Imran Aziz and colleagues. Authors attempted to resolve uncertainties about this newly recognized entity. Advising patients to stick to a gluten free diet for life is a decision that should not be considered lightly. The big challenge we face is to diagnose true gluten sensitivity as it is well known that stopping fermentable fructans (present in wheat) improves symptoms of irritable bowel syndrome. There is a great need to focus research to identify serological markers to identify this condition accurately. Equally important is to establish objective criteria to assess the response to a gluten free diet rather than relying on subjective improvement in patients' symptoms.
yours faithfully
Sauid Ishaq
sauid@doctors.org.uk
1-Aziz I, Hadjivassiliou M, Sanders D. Does gluten sensitivity in the absence of coeliac disease exist? BMJ 2012; 345: e790
Competing interests: No competing interests