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Letters Early fluid resuscitation in severe trauma

Evidence for damage control resuscitation is lacking

BMJ 2012; 345 doi: (Published 30 October 2012) Cite this as: BMJ 2012;345:e7205
  1. Matthew D Wiles, consultant neuroanaesthetist
  1. 1Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield S10 2JF, UK
  1. matthew.wiles{at}

The authors of this clinical review advocate damage control resuscitation (DCR) and permissive hypotension in multiply injured patients,1 but good evidence is lacking.

Much of the evidence for permissive hypotension has been extrapolated from animal studies. Although the largest human study cited by the authors suggested some benefit from a DCR strategy, there were …

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