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Research

Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial

BMJ 2012; 345 doi: https://doi.org/10.1136/bmj.e6409 (Published 09 October 2012) Cite this as: BMJ 2012;345:e6409

Rapid Response:

Re: Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial

Sir, Dr Schierbeck is correct that the methods of her paper made clear that this was a secondary analysis of a trial done to test a different hypothesis.

However whoever wrote the BMJ press release, which includes the following sentence, did not.

“So authors from Denmark carried out a randomised trial over 10 years with additional six years of follow-up to establish whether HRT can reduce cardiovascular risk if it is started early after menopause”.

This is misleading and has encouraged naive journalists to write headlines suggesting that the cardiovascular risks of HRT have somehow been proven to have been false. Even Dr Schierbeck and her colleagues would surely not claim this.

Competing interests: No competing interests

05 November 2012
Jim G Thornton
Professor of obstetrics and gynaecology
University of Nottingham
Hucknall Road. Nottingham