Intended for healthcare professionals

Letters Drugs for opioid dependence

Rifampicin reduces methadone concentrations

BMJ 2012; 344 doi: (Published 19 June 2012) Cite this as: BMJ 2012;344:e4199
  1. Martin John Dedicoat, infectious disease consultant1
  1. 1Heartlands Hospital, Birmingham, UK
  1. mdedicoat{at}

This useful review of the drugs used to manage opiate dependence mentions interactions with other prescribed drugs that can lead to increased sedation.1 It is also important …

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