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Letters Metal-on-metal hip implants

BMJ’s reply to DePuy’s criticisms of article on safety of metal-on-metal hip implants

BMJ 2012; 344 doi: (Published 08 May 2012) Cite this as: BMJ 2012;344:e3224
  1. Deborah Cohen, investigations editor1
  1. 1BMJ, London WC1H 9JR, UK
  1. dcohen{at}

The response from DePuy representatives Graham Isaac and Simon Sinclair sidesteps the substantive concerns described in the BMJ feature on the safety of metal-on-metal hip implants.1 2 3

The main thrust of the article was the laxity of medical device regulation: a whole class of implant—in this case large diameter metal-on-metal total hip replacement—was allowed to enter the global market without any clinical studies to assess their safety and effectiveness.

The authors acknowledge that “constituents of cobalt and chromium …

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