BMJ’s reply to DePuy’s criticisms of article on safety of metal-on-metal hip implantsBMJ 2012; 344 doi: https://doi.org/10.1136/bmj.e3224 (Published 08 May 2012) Cite this as: BMJ 2012;344:e3224
- Deborah Cohen, investigations editor1
- 1BMJ, London WC1H 9JR, UK
The response from DePuy representatives Graham Isaac and Simon Sinclair sidesteps the substantive concerns described in the BMJ feature on the safety of metal-on-metal hip implants.1 2 3
The main thrust of the article was the laxity of medical device regulation: a whole class of implant—in this case large diameter metal-on-metal total hip replacement—was allowed to enter the global market without any clinical studies to assess their safety and effectiveness.
The authors acknowledge that “constituents of cobalt and chromium …