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Avoid antimuscarinic drugs in people with dementia

BMJ 2012; 344 doi: (Published 08 May 2012) Cite this as: BMJ 2012;344:e3063
  1. Rich Braithwaite, consultant old age psychiatrist1
  1. 1Isle of Wight NHS Trust, St Mary’s Hospital, Newport PO30 5TG, UK
  1. richard.braithwaite{at}

Robinson and Cardozo understate the effects of antimuscarinic drugs on cognition, especially in those with underlying dementia.1 The small randomised studies quoted, which showed low rates of cognitive disturbance, excluded patients with dementia. Yet older people with dementia …

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