Intended for healthcare professionals

Endgames Statistical Question

The healthy entrant effect

BMJ 2012; 344 doi: (Published 18 April 2012) Cite this as: BMJ 2012;344:e2728
  1. Philip Sedgwick, senior lecturer in medical statistics
  1. 1Centre for Medical and Healthcare Education, St George’s, University of London, Tooting, London, UK
  1. p.sedgwick{at}

Researchers investigated the association between individual components of the Mediterranean diet and mortality. A prospective cohort study design was used. Participants were 23 349 men and women living in Greece. Men and women with a diagnosis of cancer, coronary heart disease, or diabetes were not recruited to the study. The primary outcome was length of time until death from any causes.1

The cohort was followed for a mean of 8.5 years, during which 1075 deaths from any causes were recorded. Those components of the Mediterranean diet that predicted reduced mortality were moderate consumption of alcohol, low consumption of meat and meat products, and high consumption of vegetables, fruits and nuts, olive oil, and legumes. However, the results …

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