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Opinion in this communication required little amendments. Authors’ are right that differences in male female morbidity and mortality are result of biological and environmental factors. Even in the womb male foetuses have higher mortality rate than their female counterparts. Environmental factors, as material, culture psychological factors, affect both the male and female to varying extents due to the biological and there by behavioural differences of the male female, and accordingly influence life expectancy morbidity and mortality rates. Death is never premature, but post a post maturation or accidental disruption of the integrated live biological functioning of the male female or hermaphrodite being, irrespective of the male female or mid sex unhealthy behaviors. No harm trying evidence based priorities for the three, instead of one or two of them, and without raising alarms for any one.