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Fibre and prevention of chronic diseases

BMJ 2011; 343 doi: (Published 10 November 2011) Cite this as: BMJ 2011;343:d6938
  1. Anne Tjønneland, professor and head of unit,
  2. Anja Olsen, project office manager
  1. 1Institute of Cancer Epidemiology, Danish Cancer Society, 2100 Copenhagen, Denmark
  1. annet{at}

Fibre specifically from cereals and whole grains is most effective in reducing risk

In the linked systematic review and meta-analysis (doi:10.1136/bmj.d6617), Aune and colleagues assess the association between the intake of dietary fibre and whole grains and the risk of colorectal cancer.1

It was first hypothesised in 1988 that food items rich in dietary fibre may prevent colorectal cancer,2 but randomised trials studying dietary fibre have not supported the association.3 This is a classic situation within nutritional epidemiology; a food item is related to decreased incidence of disease and the biological effect is attributed to a single component, but when this component is tested in randomised trials the results are not what was expected. This ought to have taught researchers to study the dietary sources and not only one specific component, which is exactly what Aune and colleagues have done.1 Their systematic review and meta-analysis of prospective observational studies clearly shows that a high intake of fibre from cereals and high consumption of wholegrain foods is …

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