BMJ 2011; 343 doi: https://doi.org/10.1136/bmj.d6855 (Published 26 October 2011) Cite this as: BMJ 2011;343:d6855

Of 4705 cases of spontaneous abortion, researchers found that 352 (7.5%) had been exposed to non-aspirin, non-steroidal anti-inflammatory drugs during pregnancy, compared with 1213 (2.6%) of 47 050 controls. Adjusting for confounding factors, any exposure to non-steroidal drugs in pregnancy was significantly associated with an increased risk of spontaneous abortion. No dose-response effect was identified (CMAJ 2011;183:1713-20, doi:10.1503/cmaj.110454).

Women with overactive thyroid glands say that the most bothersome symptom affecting the lower urinary tract is incontinence, but objective data are scarce. Over 10 000 women with hyperthyroidism were compared with matched controls without hyperthyroidism (Clinical Endocrinology 2011;75:704-8, doi:10.1111/j.1365-2265.2011.04126.x). Both cohorts were tracked for three years. One hundred and seventy three (1.6%) women in the hyperthyroid group developed urinary incontinence compared with 560 (1.04%) in the control group. After adjusting for hysterectomy and obesity, the researchers concluded that women with hyperthyroidism had a small increased risk of urinary incontinence.

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