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Letters Role of comparative efficacy

No comparative drug efficacy without legislation

BMJ 2011; 343 doi: (Published 27 September 2011) Cite this as: BMJ 2011;343:d6134
  1. Marcus Müllner, head1
  1. 1Austrian Medicines and Medical Devices Agency (AGES PharmMed), 1030 Vienna, Austria
  1. marcus.muellner{at}

Data on the comparative efficacy of drugs—or relative efficacy, as it is termed in the EU1—are certainly needed.2 Apart from the pitfalls addressed by Sorenson and colleagues,2 the political reality is that comparative efficacy is required for national reimbursement decisions, which, not surprisingly, are fiercely defended by member states. In 2009 the EU consensus was …

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