Intended for healthcare professionals

Letters Reducing population salt intake

Authors’ reply to Graudal and Jürgens

BMJ 2011; 343 doi: (Published 27 September 2011) Cite this as: BMJ 2011;343:d6121
  1. Francesco P Cappuccio, Cephalon professor of cardiovascular medicine and epidemiology, head of WHO collaborating centre1,
  2. Simon Capewell, chair of clinical epidemiology2,
  3. Paul Lincoln, chief executive3,
  4. Klim McPherson, visiting professor of public health epidemiology4
  1. 1University of Warwick, Warwick Medical School, WHO Collaborating Centre for Nutrition, Coventry CV2 2DX, UK
  2. 2University of Liverpool, Liverpool, UK
  3. 3National Heart Forum, London, UK
  4. 4University of Oxford, Oxford, UK
  1. f.p.cappuccio{at}

Graudal and Jürgens’s first statement is incorrect.1 The TOHP Trial, for example, was carried out on a background of a contemporary American diet with an average baseline daily sodium intake of 150-180 mmol. An average moderate reduction of 33-44 mmol/day reduced cardiovascular disease outcomes by 52% and 21% and all cause mortality by 24% and 17% at 18 months and 3-4 years, respectively.

The Belgian study achieved no difference in salt intake, so unsurprisingly no effect was seen on measured …

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