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Letters Vertebral fracture treatment

Current evidence does not support a role for vertebroplasty

BMJ 2011; 343 doi: (Published 10 August 2011) Cite this as: BMJ 2011;343:d5043
  1. Rachelle Buchbinder, director and professor1,
  2. Paul Glasziou, professor of evidence based medicine2
  1. 1Monash Department of Clinical Epidemiology, Cabrini Institute Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, VIC, Australia
  2. 2Centre for Research in Evidence-Based Practice, Faculty of Health Sciences, Bond University, Gold Coast, QLD, Australia
  1. rachelle.buchbinder{at}

Current evidence does not support a role for vertebroplasty in vertebral fracture.1 Combined data from the two most methodologically sound trials to date found that vertebroplasty conferred no benefit over a sham procedure; this result was consistent across subgroups, including people with symptoms for longer than six weeks.2 Most, if not all, published controlled trials of vertebroplasty for osteoporotic vertebral …

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