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Letters Fall prevention with vitamin D

Institute of Medicine responds

BMJ 2011; 342 doi: (Published 28 June 2011) Cite this as: BMJ 2011;342:d4046
  1. J Christopher Gallagher, professor of medicine, director1,
  2. Clifford Rosen, professor of medicine2
  1. 1Bone Metabolism Unit, Creighton University Medical School, Omaha, NE, USA
  2. 2Tufts University School of Medicine, Boston, MA, USA
  1. jcg{at}

The Institute of Medicine (IOM) criticised inconsistencies and misrepresentations of data in the meta-analysis of vitamin D and fall prevention by Bischoff-Ferrari and colleagues.1 2 The authors replied to the IOM,3 and we respond to them as members of the IOM committee.

In assessing the dose-response relation between vitamin D dose, serum 25-hydroxyvitamin D concentration, and risk of a fall the authors opted to compare subgroups of studies above or below a cut off point of vitamin D dose and serum 25 hydroxyvitamin …

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