Intended for healthcare professionals

Letters Calcium, vitamin D, and risk

Authors’ reply

BMJ 2011; 342 doi: (Published 07 June 2011) Cite this as: BMJ 2011;342:d3544
  1. Mark J Bolland, senior research fellow1,
  2. Alison Avenell, clinical senior lecturer2,
  3. Andrew Grey, associate professor of medicine1,
  4. Greg D Gamble, biostatistician1,
  5. Ian R Reid, professor of medicine1
  1. 1Department of Medicine, University of Auckland, Private Bag 92 019, Auckland 1142, New Zealand
  2. 2Health Services Research Unit, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK
  1. m.bolland{at}

Black suggests that personal use of calcium supplements prevents cardiovascular events, unfortunately ignoring important differences in baseline cardiovascular risk between users and non-users: users were older but had lower body mass index, blood pressure, smoking rates, and less frequent history of cardiovascular disease than non-users.1 Thus, personal calcium supplement use is a marker of lower cardiovascular disease risk, and the observed lower incidence of cardiovascular …

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