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Endgames Statistical Question

Open label trials

BMJ 2011; 342 doi: (Published 08 June 2011) Cite this as: BMJ 2011;342:d3427
  1. Philip Sedgwick, senior lecturer in medical statistics
  1. 1Section of Medical and Healthcare Education, St George’s, University of London, Tooting, London, UK
  1. p.sedgwick{at}

Researchers assessed the effectiveness of a supervised exercise programme for the treatment of patellofemoral pain syndrome. An open label randomised controlled trial was performed. Participants with a new episode of patellofemoral pain syndrome were recruited by general practitioners or sport physicians. The intervention group received a six week standardised exercise programme tailored to individual performance and supervised by a physical therapist; people in this group were instructed to practise the personalised exercises at home for three months. The control group received usual care, comprising a “wait and see” approach of rest …

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