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Letters Acute bronchiolitis

Authors’ reply

BMJ 2011; 342 doi: (Published 31 May 2011) Cite this as: BMJ 2011;342:d3350
  1. Lisa Hartling, assistant professor1,
  2. Ricardo M Fernandes, PhD student2,
  3. Liza Bialy, project coordinator1,
  4. Andrea Milne, research assistant1,
  5. David Johnson, professor3,
  6. Amy Plint, associate professor4,
  7. Terry P Klassen, professor5,
  8. Ben Vandermeer, biostatistician1
  1. 1Alberta Research Centre for Health Evidence, Department of Pediatrics, University of Alberta, 11402 University Avenue, Edmonton, AB, Canada T6G 2J3
  2. 2Gulbenkian Program for Advanced Medical Education; Child and Family Department, Hospital de Santa Maria; Clinical Pharmacology and Therapeutics, Institute of Molecular Medicine, Lisbon, Portugal
  3. 3Department of Pediatrics and Department of Physiology and Pharmacology, University of Calgary and Alberta Children’s Hospital, Calgary, AB, Canada
  4. 4Department of Pediatrics and Department of Emergency Medicine, University of Ottawa, Ottawa, ON, Canada
  5. 5Manitoba Institute of Child Health, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada
  1. hartling{at}

Our paper was not a Cochrane review,1 although it builds on several and adds a network analysis.

To minimise bias we used a predefined protocol developed with physicians and stakeholders which had predefined inclusion criteria for population, interventions, and outcomes.

A priori we decided to focus on first time wheezers. The first episode of wheezing may prove to be the first manifestation of a range …

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