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Letters The pill and thrombosis

Venous thromboembolism is egregiously underestimated

BMJ 2011; 342 doi: (Published 31 May 2011) Cite this as: BMJ 2011;342:d3344
  1. Samuel Shapiro, epidemiologist and emeritus professor1
  1. 1Boston University, Boston, MA, USA
  1. samshap{at}

The two papers on oral contraceptives and thrombosis egregiously underestimated the incidence of venous thromboembolism (VTE), making the results impossible to interpret.1 2

In Jick and Hernandez’s report the incidence rates of idiopathic plus non-idiopathic VTE in drosperinone and levonorgestrel users were 5.0 per 10 000 women years (idiopathic cases comprised 61% of total …

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