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Letters Fall prevention with vitamin D

Authors’ reply

BMJ 2011; 342 doi: (Published 03 May 2011) Cite this as: BMJ 2011;342:d2608
  1. H A Bischoff-Ferrari, director of centre on aging and mobility1,
  2. W C Willett, Fredrick John Stare professor of epidemiology and nutrition, and chair2,
  3. J E Orav, associate professor of biostatistics3,
  4. D P Kiel, associate professor of medicine4,
  5. B Dawson-Hughes, director of bone metabolism laboratory5
  1. 1University of Zurich, Zurich, and Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland
  2. 2Department of Nutrition, Harvard School of Public Health, Boston, USA
  3. 3Department of Biostatistics, Harvard School of Public Health, Boston, USA
  4. 4Hebrew Senior Life Institute for Aging Research, Harvard Medical School, Boston, USA
  5. 5USDA Human Nutrition Research Center on Aging, Tufts University, Boston, USA
  1. Heike.Bischoff{at}

We clarify three issues raised by the recent Institute of Medicine report concerning our 2009 meta-analysis of vitamin D and fall prevention.1 2 3

Firstly, the report questioned the inclusion of Broe et al, which did not pre-specify falls as a primary or secondary outcome.4 Although this violated our inclusion criteria, the Broe et al study had high quality fall assessment throughout the trial. It qualified for the primary analysis in all …

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