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New findings on H1N1 vaccine prompt revised prescribing advice

BMJ 2011; 342 doi: (Published 18 April 2011) Cite this as: BMJ 2011;342:d2524
  1. Geoff Watts
  1. 1London

New findings on the suspected link between the H1N1 vaccine Pandemrix and narcolepsy in children and adolescents have prompted the European Medicines Agency to recommend interim changes to its product information.

The findings in question are the preliminary results of a Swedish registry study of a group of children and adolescents aged under 20 years who received Pandemrix between October 2009 and December 2010. The number of cases of narcolepsy in this group was four times the number in an unvaccinated group of the same age (4.1 cases per 100 000 …

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