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Stroke patients take part in “milestone” UK trial of stem cell therapy

BMJ 2010; 341 doi: (Published 16 November 2010) Cite this as: BMJ 2010;341:c6574
  1. Jacqui Wise
  1. 1London

Doctors in Glasgow have administered stem cell therapy to a patient who became disabled after an ischaemic stroke as part of a groundbreaking trial.

The pilot investigation of stem cells in stroke (PISCES) is thought to be the world’s first fully regulated clinical trial of a neural stem cell therapy for disabled stroke patients. It is the first stem cell based clinical trial to have received regulatory approval in the United Kingdom.

The trial’s lead investigator, Keith Muir, said, “Stroke is a common and serious condition that leaves a large number of people with significant disability. In this trial we are seeking to establish the safety and feasibility of stem cell implantation, which will require careful follow-up of the patients who take part.”

Professor Muir, who holds the Sinapse chair of clinical imaging at the University of Glasgow’s Institute of Neuroscience and Psychology, added, “We hope that in future it will lead on to larger studies to determine the effects of stem cells on the disabilities that result from stroke.” …

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