Letters Oral rehydration solution risk

Link with hypernatraemic dehydration in gastroenteritis

BMJ 2010; 341 doi: https://doi.org/10.1136/bmj.c6166 (Published 02 November 2010) Cite this as: BMJ 2010;341:c6166
  1. K J Lidefelt, paediatrician1,
  2. J Giesecke, medical student,
  3. H Overödder, paediatrician1,
  4. M Brytting, assistant professor2,
  5. T Casswall, paediatrician1,
  6. C Marcus, professor1
  1. 1Karolinska University Hospital, Karolinska Institute, SE-14186 Stockholm, Sweden
  2. 2Swedish Institute for Infectious Disease Control, Stockholm, Sweden
  1. karl-johan.lidefelt{at}karolinska.se

Each year many small children fall ill with viral gastroenteritis, most often caused by rotavirus. Hypernatraemic dehydration (serum sodium ≥150 mmol/l) may ensue, which can cause hypovolaemic shock, seizures, and death. Oral or enteral fluid rehydration, or both, with a balanced sodium-glucose oral rehydration solution is recommended firstline treatment of gastroenteritis at home and in hospital.1 2

In January 2010 we observed that several initially normonatraemic infants developed increased stool losses and hypernatraemic dehydration during ongoing enteral (nasogastric …

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