Letters
Calcium and heart attacks
Making too much of a weak case
BMJ 2010; 341 doi: https://doi.org/10.1136/bmj.c4997 (Published 15 September 2010) Cite this as: BMJ 2010;341:c4997- B E Christopher Nordin, professor1,
- Robin M Daly, director of research2,
- John Horowitz, head of cardiology3,
- Andrew V Metcalfe, associate professor4
- 1Endocrine and Metabolic Unit, Royal Adelaide Hospital; Discipline of Medicine, University of Adelaide, Adelaide, SA 5005, Australia
- 2Department of Medicine, University of Melbourne, Western Hospital, Melbourne, VIC 3011, Australia
- 3Queen Elizabeth Hospital, Woodville South, SA 5011
- 4Discipline of Statistics, School of Mathematical Sciences, University of Adelaide, Adelaide, SA 5005
- christopher.nordin{at}health.sa.gov.au
The paper by Bolland and colleagues is seriously flawed in many respects, the first being its misleading title.1 It is not a meta-analysis in the usually accepted sense—that is, a review of published trials. Most of the data are unpublished, were obtained by direct request from the relevant authors, and are impossible to investigate independently.
The review provides some …
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