Journal expresses concern about validity of breast cancer studyBMJ 2010; 341 doi: https://doi.org/10.1136/bmj.c4056 (Published 26 July 2010) Cite this as: BMJ 2010;341:c4056
- Susan Mayor
Lancet Oncology has issued an “expression of concern” about the validity of a paper it published in 2007 showing that gene signatures predict the response of breast cancer to neoadjuvant chemotherapy (www.thelancet.com/journals/lanonc/article/PIIS1470-2045(10)70185-6/fulltext). It issued the notice after the authors responsible for the statistical analysis failed to respond to queries about their methods and one author was suspended from his university post.
Two of the study’s authors—Richard Iggo, from the University of St Andrews, Scotland, and Hervé Bonnefoi, from Geneva …