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Letters Second generation mephedrone

The confusing case of NRG-1

BMJ 2010; 341 doi: (Published 06 July 2010) Cite this as: BMJ 2010;341:c3564
  1. Simon D Brandt, senior lecturer in analytical chemistry1,
  2. Harry R Sumnall, reader in substance use2,
  3. Fiona Measham, senior lecturer in criminology3,
  4. Jon Cole, reader in psychology4
  1. 1School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool L3 3AF
  2. 2Centre for Public Health, Liverpool John Moores University, Liverpool L3 2AJ
  3. 3Department of Applied Social Science, Lancaster University, Lancaster LA1 4YT
  4. 4School of Psychology, University of Liverpool, Liverpool L69 7ZA
  1. s.brandt{at}

    Since the recent ban on mephedrone,1 2several alternative products have been introduced on internet websites. One of the most prominently discussed second generation products is Energy 1 (NRG-1), also advertised as naphyrone (naphthylpyrovalerone, O-2482), which originated from a group of compounds previously described in the medicinal chemistry …

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