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Contaminated cell lines may have imperilled some cancer research

BMJ 2010; 340 doi: (Published 25 January 2010) Cite this as: BMJ 2010;340:c494
  1. Janice Hopkins Tanne
  1. 1New York

    An international group of scientists has warned that oesophageal cancer cell lines that have been widely used to test new treatments may have distorted results because they contained cell lines from other types of cancer.

    Writing in the Journal of the National Cancer Institute the group says, “This report is a call for all scientists to authenticate their cell lines” (doi:10.1093/jnci/djp499).

    The incidence of oesophageal cancer has risen sharply in Western countries, say the researchers, from the Erasmus Medical Center in Rotterdam and from the United …

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