Research Methods & Reporting
The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews
BMJ 2010; 340 doi: https://doi.org/10.1136/bmj.c365 (Published 15 February 2010) Cite this as: BMJ 2010;340:c365
Data supplement
Web Extra
Extra material supplied by the author
Files in this Data Supplement:
- Data Supplement - Web table A Examples of the Outcome Reporting Bias In Trials (ORBIT) study classifications
- Data Supplement - Web table B Summary of trials classified as C according to the significance of the result
Related articles
- PAPERS Published: 28 January 2005; BMJ doi:10.1136/bmj.38356.424606.8F
- Paper Published: 31 March 2005; BMJ 330 doi:10.1136/bmj.38356.424606.8F
- Research Methods & Reporting Published: 22 July 2011; BMJ 343 doi:10.1136/bmj.d4002
- Research Published: 25 August 2011; BMJ 343 doi:10.1136/bmj.d5094
- Research Published: 03 January 2012; BMJ 344 doi:10.1136/bmj.d7202
- Research Published: 03 January 2012; BMJ 344 doi:10.1136/bmj.d7762
- Research Published: 20 August 2012; BMJ 345 doi:10.1136/bmj.e5155
- Research Published: 05 November 2012; BMJ 345 doi:10.1136/bmj.e6664
- Research Published: 24 April 2013; BMJ 346 doi:10.1136/bmj.f2304
- Editorial Published: 13 June 2013; BMJ 346 doi:10.1136/bmj.f3601
- Research Published: 19 March 2014; BMJ 348 doi:10.1136/bmj.g1888
- Research Methods & Reporting Published: 02 January 2015; BMJ 349 doi:10.1136/bmj.g7647
- Research Published: 06 March 2015; BMJ 350 doi:10.1136/bmj.h1088
- Analysis Published: 03 June 2015; BMJ 350 doi:10.1136/bmj.h2463
- Research Published: 05 April 2017; BMJ 357 doi:10.1136/bmj.j1390
- Research Methods & Reporting Published: 28 September 2018; BMJ 362 doi:10.1136/bmj.k3802
- Editorial Published: 21 September 2022; BMJ 378 doi:10.1136/bmj.o2244
See more
- By not publishing good qualitative research The BMJ is not fulfilling its valuesBMJ March 15, 2016, 352 i1478; DOI: https://doi.org/10.1136/bmj.i1478
- Qualitative research and The BMJBMJ February 10, 2016, 352 i641; DOI: https://doi.org/10.1136/bmj.i641
- Case for cultural adaptation of psychological interventions for mental healthcare in low and middle income countriesBMJ December 16, 2014, 349 g7636; DOI: https://doi.org/10.1136/bmj.g7636
- Preventing bad reporting on health researchBMJ December 10, 2014, 349 g7465; DOI: https://doi.org/10.1136/bmj.g7465
- Diabetes UK responds to comments by Asimakopoulou and colleaguesBMJ January 29, 2014, 348 g1152; DOI: https://doi.org/10.1136/bmj.g1152
Cited by...
- The association between influenza vaccination, all-cause mortality and cardiovascular mortality: a protocol for a living systematic review and prospective meta-analysis
- Protocol for the development of Core Outcome Sets for Early intervention trials to Prevent Obesity in CHildren (COS-EPOCH)
- Restoring invisible and abandoned trials of gabapentin for neuropathic pain: a clinical and methodological investigation
- E-cigarette manufacturers compliance with clinical trial reporting expectations: a case series of registered trials by Juul Labs
- Heterogeneity of outcomes for intraoperative music interventions: a scoping review and evidence map
- Methods matter: pilot and feasibility studies in sports medicine
- Assessing the relevance and uptake of core outcome sets (an agreed minimum collection of outcomes to measure in research studies) in Cochrane systematic reviews: a review
- Core outcome set in paediatric sepsis in low- and middle-income countries: a study protocol
- Outcome reporting bias in Cochrane systematic reviews: a cross-sectional analysis
- Inconsistent outcome reporting in large neonatal trials: a systematic review
- Effectiveness of influenza vaccines in adults with chronic liver disease: a systematic review and meta-analysis
- Diagnostic performance of the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation at estimating glomerular filtration rate in adults with diabetes mellitus: a systematic review and meta-analysis protocol
- Compromising Outcomes
- Establishing a core outcome set for treatment of uncomplicated appendicitis in children: study protocol for an international Delphi survey
- Outcomes reported in randomised clinical trials of major depressive disorder treatments in adolescents: a systematic scoping review protocol
- Effectiveness of intravenous albumin therapy to prevent spontaneous bacterial peritonitis, renal dysfunction and death in adults with cirrhosis: a protocol for a systematic review
- Outcome reporting bias in trials: a methodological approach for assessment and adjustment in systematic reviews
- Core Outcome Sets
- Effectiveness of pneumococcal and influenza vaccines to prevent serious health complications in adults with chronic liver disease: a protocol for a systematic review
- Tools for assessing risk of reporting biases in studies and syntheses of studies: a systematic review
- Cerebrovascular Outcomes With Proton Pump Inhibitors and Thienopyridines: A Systematic Review and Meta-Analysis
- Perspectives of survivors, families and researchers on key outcomes for research in acute respiratory failure
- Primary outcomes reporting in trials of paediatric type 1 diabetes mellitus: a systematic review
- Core outcome research measures in anal cancer (CORMAC): protocol for systematic review, qualitative interviews and Delphi survey to develop a core outcome set in anal cancer
- Meta-analysis using individual participant data from randomised trials: opportunities and limitations created by access to raw data
- Development of core outcome sets for effectiveness trials of interventions to prevent and/or treat delirium (Del-COrS): study protocol
- Systematic review protocol assessing the processes for linking clinical trial registries and their published results
- Is there an association between tendinopathy and diabetes mellitus? A systematic review with meta-analysis
- Feasibility study to examine discrepancy rates in prespecified and reported outcomes in articles submitted to The BMJ
- Clinical impact of neoadjuvant treatment in resectable pancreatic cancer: a systematic review and meta-analysis protocol
- From Protocols to Publications: A Study in Selective Reporting of Outcomes in Randomized Trials in Oncology
- Occurrence and determinants of selective reporting of clinical drug trials: design of an inception cohort study
- Uptake of systematic reviews and meta-analyses based on individual participant data in clinical practice guidelines: descriptive study
- Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation
- The knowledge system underpinning healthcare is not fit for purpose and must change
- Reporting of harms in systematic reviews and their primary studies
- Selective reporting bias of harm outcomes within studies: findings from a cohort of systematic reviews
- Fructose, high-fructose corn syrup, sucrose, and nonalcoholic fatty liver disease or indexes of liver health: a systematic review and meta-analysis
- How does under-reporting of negative and inconclusive results affect the false-positive rate in meta-analysis? A simulation study
- Variation of clinical outcomes used in glaucoma randomised controlled trials: a systematic review
- Antidepressant efficacy of agomelatine: meta-analysis of published and unpublished studies
- Interventions to Improve Cortisol Regulation in Children: A Systematic Review
- Survey of the Reporting Characteristics of Systematic Reviews in Rehabilitation
- Reporting of harms data in RCTs: a systematic review of empirical assessments against the CONSORT harms extension
- Selective reporting of outcomes in randomised controlled trials in systematic reviews of cystic fibrosis
- The HONEYPOT Randomized Controlled Trial Statistical Analysis Plan
- Restoring the integrity of the clinical trial evidence base
- Influence of trial sample size on treatment effect estimates: meta-epidemiological study
- Knowledge Integration in Cancer: Current Landscape and Future Prospects
- Melatonin for sleep problems in children with neurodevelopmental disorders: randomised double masked placebo controlled trial
- Reporting of conflicts of interest from drug trials in Cochrane reviews: cross sectional study
- Standard 5: Selection, Measurement, and Reporting of Outcomes in Clinical Trials in Children
- Outcome reporting bias in evaluations of public health interventions: evidence of impact and the potential role of a study register
- The truth, but not the whole truth? Call for an amnesty on unreported results of public health interventions
- Homeopathic medicines for children
- Consistency in the Analysis and Reporting of Primary End Points in Oncology Randomized Controlled Trials From Registration to Publication: A Systematic Review
- Bias in systematic reviews?
- Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials
- Frequency and reasons for outcome reporting bias in clinical trials: interviews with trialists
- Assessment of publication bias, selection bias, and unavailable data in meta-analyses using individual participant data: a database survey
- Effect of reporting bias on meta-analyses of drug trials: reanalysis of meta-analyses