Intended for healthcare professionals

Letters Vitamin B-12 deficiency

Consider non-invasive follow-up and malabsorption in old age

BMJ 2010; 340 doi: (Published 22 June 2010) Cite this as: BMJ 2010;340:c3323
  1. Jörn Schneede, associate professor1
  1. 1Department of Clinical Pharmacology, NUS, SE-90185 Umeå, Sweden
  1. jorn.schneede{at}

    Hudson describes the classic clinical signs of vitamin B-12 deficiency in an elderly patient and recommends traditional diagnostic procedures such as measuring vitamin B-12 values and determining antibodies against intrinsic factor and parietal cells.1 However, old age itself poses a dilemma for further diagnostic strategies.2 Of course, invasive procedures such as gastroscopy and bone …

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