Intended for healthcare professionals

Letters Withdrawal of sibutramine

Author’s reply

BMJ 2010; 340 doi: (Published 10 March 2010) Cite this as: BMJ 2010;340:c1349
  1. Gareth Williams, professor of medicine1
  1. 1Faculty of Medicine and Dentistry, University of Bristol, Bristol BS10 5NB
  1. gareth.williams{at}

    Finer and colleagues’ spirited letter might stimulate a wider and long overdue debate on the lasting benefits of the modest reduction in fat mass achievable with any of the anti-obesity drugs in clinical practice.1

    For an obese adult weighing 70 kg aged 20 who gains 30 kg of fat through adult life, a 10% loss of weight lasting two years is only a 3% reduction in the total excess fat carried until …

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