Microbicide offers no protection against HIV infection

BMJ 2009; 339 doi: (Published 18 December 2009) Cite this as: BMJ 2009;339:b5538
  1. Bob Roehr
  1. 1Washington DC

    There has been another setback in efforts to develop a microbicide to protect women against HIV infection during vaginal sex. Results of a large clinical trial of PRO 2000, released on 14 December, showed that although the product was safe, it was not effective against infection.

    The large (9385 women) double blind, placebo controlled trial (called MDP 301) was conducted by the Microbicides Development Programme—a broad international collaboration—in South Africa, Tanzania, Uganda, and Zambia. It had substantial support …

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