Intended for healthcare professionals

Letters Seeding trials

Just say no

BMJ 2009; 339 doi: (Published 02 November 2009) Cite this as: BMJ 2009;339:b4527
  1. David Egilman, clinical associate professor
  1. 1Brown University, Department of Community Health, 8 North Main Street, Attleboro, MA 02703, USA
  1. david{at}

    The postmarketing observational studies referred to by Annette Tufts in her news story are sham studies that are generally referred to as “seeding trials.”1 2 The actual research taking place is the evaluation of the return on investment (ROI) …

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