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Meyer and Köpke urge us to consider "side effects of vitamin D and
But the doses involved ( vitamin D of 400 - 1100 IU) in Bischoff-Ferrari's
analysis in the BMJ of 1 Oct 09 and in the quoted reference ( Avenell
side-effects are certainly not toxic. Older advise for the tolerable
level for vitamin D was 2000 IU, newer evidence exists for the safety for
higher doses, 10,000 IU daily, (Vieth 2009). And concerning side effects
the quoted reference (Avenell 2009) gastro-intestinal symptoms and renal
calculi are clearly in the vast majority due to the added calcium or the
calcitriol- not due to vitamin D.
No competing interests
09 November 2009
Helga M Rhein
Sighthill Health Centre, Calder Rd, Edinburgh EH11 4AU