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International trials registry is missing important information, study finds

BMJ 2009; 339 doi: (Published 07 September 2009) Cite this as: BMJ 2009;339:b3627
  1. Jacqui Wise
  1. 1London

    Researchers have found that important information is missing from many trials recorded on the international register of clinical trials, a publicly accessible database of clinical trials managed by the US National Library of Medicine.

    Joseph Ross, assistant professor of geriatrics at the Mount Sinai School of Medicine, New York, and colleagues sampled a cross section of trials on the registry. After excluding phase I safety trials, they identified 7515 trials that were registered within after 31 December 1999 and whose record indicated trial completion by 8 June 2007.

    All of the trials reported the essential information required by the registry, but optional data including the primary outcome of …

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