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Letters QRISK validation and evaluation

ASSIGN, QRISK, and validation

BMJ 2009; 339 doi: (Published 01 September 2009) Cite this as: BMJ 2009;339:b3514
  1. Hugh Tunstall-Pedoe, professor emeritus and senior research fellow1,
  2. Mark Woodward, senior research fellow (and Mount Sinai School of Medicine, New York)1,
  3. Graham Watt, professor2
  1. 1Cardiovascular Epidemiology Unit, Institute for Cardiovascular Research, Ninewells Hospital, University of Dundee, Dundee DD1 9SY
  2. 2General Practice and Primary Care, University of Glasgow
  1. h.tunstallpedoe{at}

    We challenge the recent QRISK validation and editorial concluding that QRISK is the cardiovascular risk score for the United Kingdom.1 2

    ASSIGN, QRISK’s precursor, was launched in Scotland before QRISK appeared.3 Predicting that scores omitting social deprivation (socioeconomic status) as a risk factor could exacerbate social gradients in disease, we developed ASSIGN to include it. ASSIGN was adopted without external validation …

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