Intended for healthcare professionals

Endgames Statistical question

Study design

BMJ 2009; 339 doi: (Published 15 July 2009) Cite this as: BMJ 2009;339:b2793
  1. Philip Sedgwick, senior lecturer in medical statistics
  1. 1Centre for Medical and Healthcare Education, St George’s, University of London, Tooting, London SW17 0RE
  1. p.sedgwick{at}

    A randomised double blind trial compared the effects and tolerability of omeprazole and cisapride for the management of heartburn. Which of the following statements best describe the rationale for conducting this trial using the double blind technique?

    • a) Elimination of allocation bias

    • b) Minimisation of confounding between treatment groups

    • c) Minimisation of response bias

    • d) Minimisation of assessment bias


    c …

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