Intended for healthcare professionals


Resistance of flu virus to oseltamivir is growing, US study shows

BMJ 2009; 338 doi: (Published 12 March 2009) Cite this as: BMJ 2009;338:b995
  1. Susan Mayor
  1. 1London

    Influenza A viruses that are resistant to oseltamivir (Tamiflu) are becoming more prevalent, the latest figures from the United States show.

    Nearly all (98.5%) of influenza A (H1N1) viruses tested from the early 2008-9 flu season were resistant to oseltamivir (JAMA 2009;301:1034-41, doi:10.1001/jama.2009.294). In the previous year 12% of these viruses were found to be resistant to the drug. The viruses were tested as part of ongoing surveillance by the Centers for Disease Control and Prevention (CDC), Atlanta.

    The increase in drug resistance prompted the CDC to issue interim guidance to doctors at the end of 2008 recommending that …

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