NHS needs to prepare for era of non-invasive fetal DNA tests
BMJ 2009; 338 doi: https://doi.org/10.1136/bmj.b618 (Published 13 February 2009) Cite this as: BMJ 2009;338:b618- Susan Mayor
- 1London
The NHS should take steps to respond to new types of fetal testing set to become increasingly available in the next few years, an expert group has recommended in a report published this week.
Non-invasive prenatal diagnosis uses cell-free fetal DNA that circulates in the mother’s blood during pregnancy. It can be used in several ways, including determination of fetal sex by detecting male Y chromosome DNA in fetuses at risk of a sex linked disease; diagnosing some single gene disorders; detection of an abnormal ratio of chromosomes, such as in Down’s syndrome; and determination of blood type in fetuses at risk of incompatibility, particularly the rhesus D …
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