Intended for healthcare professionals

Letters A/H1N1 flu

Aspirin in the 1918 pandemic

BMJ 2009; 338 doi: (Published 15 June 2009) Cite this as: BMJ 2009;338:b2398
  1. Tsunetoshi Shimazu, director1
  1. 1Shimazu Clinic 31 Higashitakada-choJapan, Mibu, Nakagyo-ku, Kyoto, Japan 604-8845
  1. shimazu-clinic{at}

    Aspirin may have enhanced the virulence of the flu virus in the 1918 pandemic, which has implications for A/H1N1 flu.1

    During the 18 months of the 1918-9 pandemic, 27 million people died worldwide, mortality being highest in the second wave, October 1918, especially in the …

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