Intended for healthcare professionals

Letters Sample size calculations

Must do better

BMJ 2009; 338 doi: (Published 09 June 2009) Cite this as: BMJ 2009;338:b2323
  1. Jonathan D Mayer, professor of epidemiology1
  1. 1University of Washington, Seattle, WA 98195, USA
  1. jmayer{at}

    As a reviewer in several study sections at the US National Institutes of Health, I have noted that it is impossible to replicate sample size and power calculations in the overwhelming number of otherwise excellent research proposals.1 I then noted that replication …

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