Intended for healthcare professionals



BMJ 2009; 338 doi: (Published 08 April 2009) Cite this as: BMJ 2009;338:b1408
  1. Daniel El Fassi, MD,
  2. Ove Juul Nielsen, MD
  1. 1Department of Haematology, Rigshospitalet Copenhagen University Hospital, Copenhagen, Denmark
  1. fassi{at}

    A 35 year old pregnant woman developed gross gingival hyperplasia and lost 10 pounds (4.5 kg) in weight over five weeks. She had no other symptoms. Blood samples showed leukocytosis, anaemia, and thrombocytopenia. Bone marrow aspiration showed acute myeloblastic leukaemia. Pregnancy was terminated at around 22 weeks and chemotherapy promptly started. Her gingival hyperplasia improved within five days of starting chemotherapy (A) and by 51 days had returned to normal without any odontological intervention (B). Gingival hyperplasia is associated with acute myelomonocytic and monocytic leukaemias and necessitates immediate investigation.


    Cite this as: BMJ 2009;338:b1408


    • Patient consent obtained.

    View Abstract

    Log in

    Log in through your institution


    * For online subscription