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Effect of large doses of histamine on gastric secretion of HCl (1953)

BMJ 2009; 338 doi: (Published 01 June 2009) Cite this as: BMJ 2009;338:b1270

In the routine histamine test of gastric secretion the dose of histamine advised has been determined arbitrarily as being generally sufficient to provoke an acid response and generally free from liability to cause untoward symptoms. It is thus a compromise, and fails to take account of individual variations in susceptibility. This defect …

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