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Letters Trophoblastic disease

Analytical problems associated with HCG assay

BMJ 2008; 337 doi: (Published 13 October 2008) Cite this as: BMJ 2008;337:a2076
  1. Julian H Barth, consultant chemical pathologist1
  1. 1Leeds General Infirmary, Leeds LS1 3EX
  1. julian.barth{at}

    Sebire and Seckl state that gestational trophoblastic disease is monitored by measuring serum human chorionic gonadotrophin (HCG), but they do not discuss the analytical problems associated with this assay.1

    Numerous reports of interference with this assay have been made since 1984, …

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