Intended for healthcare professionals

Letters Sickle cell disease

Beware of transfusions and hyperhaemolysis

BMJ 2008; 337 doi: (Published 01 October 2008) Cite this as: BMJ 2008;337:a1874
  1. Amit Patel, NIHR academic clinical fellow in haematology1
  1. 1Department of Haematology, Imperial College London, Hammersmith Hospital, London W12 0NN
  1. amit.patel{at}

    de Montalembert touches on important aspects of managing sickle cell disease, including the use of red blood cell transfusion as acute or regular top-ups and red cell exchanges.1

    Hyperhaemolysis is a life threatening complication of red cell transfusions seen in 4% of paediatric and 1% of adult patients with sickle …

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