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An apoptosis investigator

BMJ 2008; 336 doi: https://doi.org/10.1136/sbmj.0803110 (Published 01 March 2008) Cite this as: BMJ 2008;336:0803110
  1. Shaheen Lakhan, executive director1
  1. 1Global Neuroscience Initiative Foundation, Los Angeles, CA, USA

Pathological apoptosis is linked to neoplasia and neurodegeneration. Sarit Larisch discovered ARTS, a mitochondrial protein involved in regulating apoptosis. Shaheen Lakhan is inspired by her passion for research and teaching

Fact file

Name—Sarit Larisch

Position—Head of the Apoptosis and Cancer Research Laboratory, Rambam Medical Center, teaching hospital of Technion, Israel Institute of Technology

Biography—Her team discovered ARTS (apoptosis related protein in transforming growth factor β signalling pathway) and found that it functions as a tumour suppressor protein. She started SimeTRA Pharm, a small biotechnology company focused on developing ARTS peptidomimetics, which penetrate cancer cells and induce selective apoptosis

What is known about apoptosis?

Apoptosis is an essential process in the development of multicellular organisms and for maintaining homoeostasis in normal cells. The roles of apoptosis include sculpting structures during development; deletion …

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