Intended for healthcare professionals

Letters Invasive meningococcal disease

Cerebral perfusion in invasive meningococcal disease

BMJ 2008; 336 doi: (Published 26 June 2008) Cite this as: BMJ 2008;336:1453
  1. Peter J Flegg, consultant physician
  1. 1Blackpool Victoria Hospital, Blackpool FY3 8NR
  1. dr.flegg{at}

I am surprised that the SIGN guidelines (and therefore this summary of them1) make no mention of the importance of adequate cerebral perfusion in those with invasive meningococcal disease. Cerebral perfusion pressure is the difference between the mean arterial pressure (which is usually low from the associated hypotensive shock) and …

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