Intended for healthcare professionals

Letters Vitamin D deficiency

More evidence is needed before general supplementation

BMJ 2008; 336 doi: (Published 26 June 2008) Cite this as: BMJ 2008;336:1451
  1. Miles D Witham, clinician scientist, ageing and health
  1. 1University of Dundee, Ninewells Hospital, Dundee DD1 9SY

Holick is right to highlight the high prevalence of vitamin D insufficiency in many groups of people living at higher latitudes.1 However, the evidence base to support general supplementation, including aggressive fortification, does not currently exist.

An impressive array of observational data suggests that low vitamin D concentrations are associated with a wide variety of diseases, including diabetes, cardiovascular disease, and cancer. …

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