Letters Tibolone

Still waiting and searching for answers

BMJ 2008; 336 doi: https://doi.org/10.1136/bmj.39423.568056.1F (Published 03 January 2008) Cite this as: BMJ 2008;336:7
  1. Emilio Maestri, endocrinologist1,
  2. Susanna Maltoni, pharmacist1,
  3. Vittorio Basevi, gynaecologist1,
  4. Annamaria Marata, clinical pharmacologist1,
  5. Nicola Magrini, head1
  1. 1CeVEAS, V le LA Muratori, 201, 41100 Modena, Italy
  1. e.maestri{at}ausl.mo.it

    Clinicians working in the subject area of menopausal problems are still waiting for answers from trials designed to give results on relevant topics in the treatment of climacteric complaints.

    Two important trials were planned (and registered) to define the efficacy and safety of tibolone versus placebo in preventing osteoporotic fractures (LIFT)1 and managing menopausal symptoms in women after treatment for breast malignancy (LIBERATE).2 The start of the two studies received great attention from the media; repeated attention was sparked by every favourable report of the study data and …

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