Intended for healthcare professionals

Letters Allergy after breast feeding

Testing hypotheses: reply

BMJ 2007; 335 doi: (Published 22 November 2007) Cite this as: BMJ 2007;335:1061
  1. Michael S Kramer, professor
  1. McGill University Faculty of Medicine, Montreal, Quebec, Canada H3H 1P3
  1. michael.kramer{at}

    Silvers et al say that our recent paper was written as if the study's main aim was to test the association between prolonged exclusive breast feeding and asthma and allergy.1 Every randomised controlled trial has a primary outcome that serves as the basis for estimating sample size requirements and for obtaining funding. But we also examined secondary outcomes in the first year of life and sought support …

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